CATCEF-O TAB
Active Ingredients:
- Cefixime (200 mg): A third-generation cephalosporin antibiotic.
- Ofloxacin (200 mg): A fluoroquinolone antibiotic.
Description & Mechanism of Action:
Cefixime:
- Works by inhibiting bacterial cell wall synthesis, leading to bacterial death.
- Effective against Gram-positive and Gram-negative bacteria.
Ofloxacin:
- A broad-spectrum antibiotic that inhibits bacterial DNA gyrase, preventing bacterial replication and growth.
- Active against both aerobic and anaerobic bacteria.
Uses:
- Respiratory infections (bronchitis, pneumonia, tonsillitis)
- Urinary tract infections (UTIs)
- Gastrointestinal infections (diarrhea, typhoid fever)
- Ear, nose, and throat infections
- Skin and soft tissue infections
- Sexually transmitted infections (gonorrhea, chlamydia)
Dosage & Administration:
- Adults: Typically one tablet twice daily or as prescribed.
- Children: Not commonly recommended; pediatric dose based on weight.
- Take after food to reduce stomach irritation.
Side Effects:
- Nausea, vomiting, diarrhea
- Stomach pain, bloating
- Headache, dizziness
- Skin rash, itching (possible allergic reactions)
- Risk of tendon rupture (rare but serious with Ofloxacin)
- Photosensitivity (avoid direct sunlight)
Precautions & Warnings:
- Avoid in severe kidney/liver disease (dose adjustment required).
- Not recommended in pregnancy & breastfeeding (consult a doctor).
- Avoid in children under 18 (risk of joint and tendon issues).
- Do not take with dairy products or antacids (reduces Ofloxacin absorption).
Drug Interactions:
- Warfarin (increased bleeding risk)
- NSAIDs (risk of seizures)
- Antacids & iron supplements (reduce Ofloxacin absorption)
- Corticosteroids (increased risk of tendon rupture)